DHEA for Menopause Relief: Healthy Hormone Balance for Energy and Well-being

As women reach their mid-30s and beyond, DHEA can be an excellent way to maintain health and well-being. Its advantages can be particularly beneficial throughout perimenopause, menopause, and post menopause providing DHEA for menopause relief. Twist 25 DHEA cream provides DHEA the right way.

Understanding DHEA

DHEA, short for dehydroepiandrosterone, is known as the “mother hormone”. It is a naturally occurring carbon chain molecule, the same in men as in women. Humans produce it naturally from the adrenal glands, gonads and dermis. DHEA is the most abundant hormone base in the human body that serves as a precursor for all sex hormones like the estrogenic hormones and testosterone. This vital pro-hormone thus plays an important part in maintaining energy, mood, sleep, and overall physiologic and mental well-being.

However, DHEA levels peak by age 25 and decline steadily with age. By age 35, people produce about 20% less DHEA than when they were 25. By age 50, DHEA levels are just half of what they were at age 25. This decline is associated with numerous symptoms associated with aging and menopause, such as:

  • Reduced energy and vitality
  • Hot flashes
  • Mood swings and irritability
  • Difficulty sleeping
  • Decreased libido
  • Loss of muscle mass and strength
  • Impaired cognitive function
  • Weakened bones

If you or anyone you know is experiencing these symptoms of midlife hormone decline, you may be wondering about the connection between DHEA and menopause symptoms. Fortunately, there is something you can do to slow down this hormone decline. Twist 25 is a DHEA supplement cream that can be applied directly on the skin as an absorbable skin cream, to help maintain healthy DHEA levels. This supports hormone metabolism and helps maintain youthful vitality. DHEA cream is both safe and effective, offering a natural way to combat the effects of hormone decline we call “aging”.

The Science of DHEA: How to use DHEA

Many studies of DHEA for menopause have been done using oral DHEA supplements, which are less effective than a DHEA cream. When DHEA is used as an oral supplement it is much less effective than when it is used as an absorbable skin cream because oral DHEA is destroyed by digestion and eliminated by the liver, limiting its absorption and effectiveness.

DHEA cream is a much better way to use DHEA because a lot of DHEA metabolism goes on naturally in the skin. So applying DHEA as an absorbable skin cream allows for much better absorption of DHEA allowing noticeable benefits for relief of symptoms of menopause.

Dr. Labrie’s Research: DHEA for Menopause Relief

Dr. Fernand Labrie, a renowned medical expert and research director at the University of Toronto Medical School, has done extensive research using DHEA cream for menopausal women. His findings show remarkable significant improvements in:

Twist 25 DHEA cream is bioidentical DHEA applied the right way to allow the benefits of DHEA to occur, providing relief from many of the unpleasant symptoms of menopause.

Why Women Choose DHEA Cream:

Twist 25 DHEA cream offers a safe, natural, and effective solution to many of the challenges menopause causes. It helps women feel revitalized, enhances their mood, and boosts their overall quality of life. Plus, it does all this with no dangerous side effects.

benefits of dhea

DHEA for Menopause Relief: A Proven Solution for Women

In a 2006 study featured in the Journal of Clinical Endocrinology & Metabolism, researchers uncovered the potential of DHEA in easing menopause symptoms. Women who took DHEA over a four week study experienced significant improvements in their quality of life, with a notable decreases in hot flashes.

feeling good with dhea for women











This study underscores DHEA’s ability to restore hormonal foundation and provide relief from the common and often troublesome symptoms of menopause. By boosting DHEA levels, women naturally produce other smaller metabolite hormones like estrogens and androgens like testosterone, which are vital for overall health and well-being.

One of the primary reasons women use DHEA is to alleviate common menopause symptoms. Twist 25 DHEA cream is a safe and effective way to boost low DHEA levels and rejuvenate their vitality. With Twist 25 DHEA cream you allow the body to naturally produce it’s own hormones.

The DHEA Decline: Understanding the Impact on Women’s Health

As women (and men) get older, DHEA levels decrease. This gradual decline typically starts in their 30s and continues throughout perimenopause and menopause, which can significantly impact their overall physiological health and how they feel.

According to research published in the Journal of Steroid Biochemistry and Molecular Biology, there’s a clear link between lowering DHEA levels and decreased production of crucial hormones like estrogen and testosterone. This hormonal imbalance can trigger numerous symptoms and health issues, such as:

  • Fatigue and low energy
  • Mood swings and irritability
  • Poor quality sleep
  • Decreased libido
  • Weight gain
  • Decreasing bone strength
  • Cognitive decline
  • Thin papery skin

Understanding the natural decline in DHEA and doing something about it is key for menopausal women seeking relief from hormone decline to maintain optimal health and happiness as they age.

The Cortisol-DHEA Imbalance from Stress and Aging

As we age, there is a gradual change in hormone production: less and less DHEA while there is more and more cortisol, the stress hormone. Modern life’s relentless pace only exacerbates this imbalance, ramping up stress levels.

Between the ages of 35 and 55, many women find themselves juggling the pressures of work, family, and personal responsibilities. This constant juggling act can lead to chronic stress and, eventually, a condition called “adrenal fatigue”, when the adrenal glands make too much cortisol and not enough DHEA to counterbalance it.

This cortisol-DHEA imbalance can seriously affect your health and well-being, resulting in:

  • Increased fatigue and exhaustion
  • Difficulty sleeping and insomnia
  • Weight gain, especially in the abdomen
  • Mood swings and irritability
  • Weakened immune function
  • Increased inflammation
  • Accelerated aging

Understanding the interplay between cortisol and DHEA is key to taking proactive steps for restoring balance and safeguarding your health.

Restoring a Healthy Balance: DHEA as the antidote to Cortisol

As we grow older and face daily stress, our body’s hormone production naturally changes. Cortisol, known as the stress hormone, tends to rise, while DHEA levels drop. This imbalance can leave us feeling drained, stressed, and susceptible to numerous health problems.

DHEA is crucial in counterbalancing the adverse effects of too much cortisol. It serves as a natural anti-inflammatory agent, aiding in healing and repair while shielding us from stress’s harmful impacts. By replenishing DHEA, we can regain hormonal balance, lessen inflammation, and enhance overall health and well-being.

Twist 25 DHEA cream provides a convenient and effective method to supplement DHEA and restore this essential balance. Research has shown that women who use DHEA cream report a renewed sense of well-being, enhanced mental clarity, increased energy, better sleep, soft well hydrated skin and improved libido.

By adding Twist 25 to your daily regimen, you can leverage the benefits of DHEA to combat the signs of aging, stress, and hormonal imbalance to improve quality of life.

Hormone Changes Through the Years

The DHEA Decline:

DHEA levels in both men and women follow a similar course, peaking in your 20s and then gradually declining at a rate of about 2% per year. For women, this decline picks up speed during perimenopause and menopause, ages 35-55, resulting in a noticeable drop in DHEA production, and other hormones.

dhea for women levels over time

The graph shown below illustrates the gradual rise and decline of DHEA levels over the course of a human lifespan combining the numbers for women and men.

dhea for women levels

When DHEA levels plummet, the risk of various health issues climbs. This situation is made worse by rising cortisol levels, often dubbed the stress hormone, creating a hormonal imbalance that can seriously affect your well-being.

The symptoms of low DHEA and high cortisol might sound all too familiar:

  • Fatigue and low energy
  • Sleep disturbances
  • Decreased libido
  • vaginal dryness, atrophy
  • Mood swings and irritability
  • Difficulty concentrating
  • Aches and pains

Women can do something to alleviate these symptoms by addressing declining DHEA levels.  Twist 25 DHEA cream provides a natural, effective way to supplement DHEA and restore this important hormonal base, allowing women to regain energy and improve mood, support healthy cardiovascular health, immune support , sex drive and quality sleep.

Beyond Menopause: DHEA’s Wide-Ranging Benefits for Women


DHEA does more than just ease menopause symptoms. DHEA also provides many other health benefits:

  • Improves Cognitive Function: DHEA aids in enhancing memory, focus, and overall brain health, helping you stay mentally agile.
  • Supports Metabolic Health: DHEA has been found to reduce both visceral and subcutaneous abdominal fat
  • Stronger Bones: DHEA supports bone density, and helps cartilage, collagen and connective tissue
  • Cardiovascular Benefits: Research indicates that DHEA can bolster heart health and lessen the risk of heart disease.
  • Immune System Support: DHEA enhances immune function, helping you fend off infections and stay well.
  • Reduced Inflammation: The anti-inflammatory properties of DHEA can help guard against chronic illnesses and assist in the healing process.
  • Vaginal Health: DHEA can soothe vaginal dryness and atrophy, enhancing comfort and sexual function.

These extensive benefits stem from DHEA’s role as a precursor hormone. It’s transformed into other crucial hormones like estrogen and testosterone, which are vital for numerous bodily functions.

Better Sleep with DHEA: Recharge Your Body and Mind

Quality sleep is crucial for maintaining overall health and well-being. Yet, it often becomes a struggle as we age, particularly for women facing menopause. Luckily, DHEA can offer some relief.

Research indicates that DHEA significantly contributes to achieving deep, restorative REM sleep. This critical sleep phase is where our bodies undergo repair and regeneration, which is essential for cognitive function, mood stability, and energy levels.

By using Twist 25 DHEA cream to replenish DHEA levels, many women report benefits such as:

Twist 25 DHEA cream provides a natural solution to the sleep issues associated with menopause and aging. By maintaining your hormones, you can improve sleep quality, energy levels, and improve your overall quality of life.

DHEA for Women: Enjoy Vitality to Embrace your Best Years

Maintaining optimal DHEA levels is crucial for women over 35, especially during and after menopause. This potent hormone can help alleviate common symptoms like hot flashes, mood swings, and sleep disturbances while also promoting overall health and well-being.

Twist 25 DHEA cream, a simple, daily application of bioidentical DHEA derived from plant sources, can help you:

  • Restore hormonal balance: Support your body’s natural hormone production and ease the symptoms of hormonal imbalance.
  • Improve sleep: Enhance sleep quality so you wake up feeling refreshed and energized.
  • Boost mood and energy: Reduce fatigue, irritability, and brain fog, while improving overall mood and mental clarity.
  • Strengthen bones and muscles: Protect against osteoporosis and maintain muscle for a strong, active lifestyle.
  • Support heart health: Reduce cardiovascular disease risk and promote healthy blood pressure and cholesterol levels.
  • Enhance immune function: Bolster the immune system to fight off infections and stay healthy.

Twist 25 was developed over 30 years ago specifically to help women experiencing symptoms of menopause. Twist 25 DHEA cream allows DHEA to be absorbed and processed in the skin. Plus, the coconut oil base cream is great for skin health too. So you feel your best and look your best with Twist 25 DHEA cream.

Ready to reclaim your vitality, enhance your well-being, and support your health to enjoy life and feel your best? Try Twist 25 DHEA cream. With consistent daily use, you can experience a significant improvement in quality of life within just a few weeks with no dangerous side effects.


Dr. Fernand Labrie. “All sex steroids are made intracellularly in peripheral tissues by the mechanisms of intracrinology after menopause”. Journal of Steroid Biochemistry & Molecular Biology. Jan. 2015;145:133-8. doi: 10.1016/j.jsbmb.2014.06.001. Epub 2014 Jun 9. PMID: 24923731. Pubmed https://pubmed.ncbi.nlm.nih.gov/24923731/

Dr. Fernand Labie, V Luu-The, A Bellanger, S-X Lin, J Simard, G Pelletier, C Labrie. “Is dehydroepiandrosterone a hormone?” Journal of Endocrinology. Nov, 2005;187(2):169-96. doi: 10.1677/joe.1.06264. Pubmed https://pubmed.ncbi.nlm.nih.gov/16293766/

Debra L. Barton, Jeff A. Sloan, Lynne T. Shuster, Paula Gill, Patricia Griffin, Kathleen Flynn, Shelby A. Terstriep, Fauzia N. Rana, Travis Dockter, Pamela J. Atherton, Michaela Tsai, Keren Sturtz, Jacqueline M. Lafky, Mike Riepl, Jacqueline Thielen, and Charles L. Loprinzi. “Evaluating the efficacy of vaginal dehydroepiandrosterone for vaginal symptoms in postmenopausal cancer survivors: NCCTG N10C1 (Alliance)” Published in final form as Support Care Cancer. 2018 Feb; 26(2): 643–650. Published online 2017 Sep 18. doi: 10.1007/s00520-017-3878-2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754227/

Hugh R. Woodward, MHA

Hugh Woodward is President/CEO of Health2Go, Inc. Health2Go makes and sells Twist 25 DHEA cream.
Hugh has a BBA in Business Management from University of Texas in Austin, Texas and an MHA, Master of Science in Health Care Administration.

Hugh is a subject matter expert on DHEA dedicating the past 20+ years of his life to studying the medical research about it. Hugh started Health2Go, Inc. in 2007 to research and develop the safest most effective DHEA supplement cream that can be made.

View profile

Leave a Comment

Your email address will not be published. Required fields are marked *

Shopping Cart