Happy healthy couple in good mood

DHEA For Mood: Enhance Your Mood With DHEA

Looking for a Mood Boost?

Feeling a little stressed and down lately? Watching the evening news these days definitely doesn’t give us much to be joyful about. We could all use a little more hope and laughter these days, especially as days begin to get shorter and it gets colder. If you’re looking for a natural way to improve your mood, DHEA for mood might be worth considering.

The Role of Hormones in Mental Health

Most of us would welcome a healthy way to do something great for our health that also helps us feel happier too. Some things that can help are talking with a friend, reading a good book, or a walk with kids or pets. Please don’t just rush to assume antidepressant medications are necessarily the answer you need to start feeling happier. One important component to remember is that our hormones play a crucial part in how we feel and function.

Why Antidepressants May Not Be the Answer

Antidepressants are not usually the best answer when it comes to mild or moderate depression. Most people who don’t have severe symptoms should first try a few simple natural options to feel happier without taking antidepressant drugs. Prescription antidepressant drugs can often have unreliable swing up then crash effects, starting an unpleasant up and down roller-coaster. First, get a basic health checkup with a healthcare provider and ask to have your hormone levels checked.

How DHEA Affects Your Mood

If you’re past age 35, before you use a prescription anti-depressant medication, please try a basic natural solution first that makes sense. For both men and women, after age 35 reduced levels of DHEA, short for dehydroepiandrosterone, is expectable. Hormone decline happens to all of us. Reduced DHEA levels yield low vitality and lack of energy and mood because DHEA is a base hormone precursor.

Twist 25  DHEA supplement cream may help you to maintain a stronger prohormone foundation to thereby subsequently to improve hormones. This boosts mood and vitality and helps you rediscover little pleasures. The joy of life.

DHEA is a pro-hormone that is naturally produced and metabolized in the adrenal glands, gonads and skin. DHEA is a precursor or base building block for the production of hormones, like testosterone and estrogens. Hormones are the drivers that control our mood.

Age-Related Decline in DHEA Levels

It’s an unfortunate fact that after people reach their mid-twenties, DHEA levels begin to diminish at a rate of about 2% per year. So by age 35, most people are making about 20% less than when they were “in their prime”. By age 50, middle age, DHEA levels are often down to about 50 percent of the optimal levels we once had in our twenty’s.

Medical science shows that maintaining strong DHEA levels can help us feel happier, more energetic and less moody throughout the day, with a greater sense of focus, and more sense of well-being and drive. Researchers have found that DHEA supplementation helps to reduce symptoms of depression for people with “the blues” who are feeling down, especially when these symptoms of depression worsen during middle age. DHEA also counterbalances the stress hormone, cortisol.

As we get older we begin to produce less and less DHEA; meanwhile, we progressively make more and more cortisol as we get older. Cortisol is the inflammatory response hormone. When we are subjected to greater stress and anxiety, we make more cortisol. So again, maintaining healthy DHEA levels every day is important to keep the negative effects of too much cortisol under control.

A team of physician researchers led by Peter Schmidt, MD, Robert C. Daly, MD, and Micki Bloch, MD conducted a five year placebo controlled study published in Journal of the American Medical Association (JAMA Network). The study found “DHEA to be an effective treatment for midlife-onset major and minor depression.” The trial conducted from January 4, 1996 through August 31, 2002 was carefully done measuring study participants symptoms of depression using the Hamilton Depression Rating Scale.

“Six weeks of DHEA administration was associated with a significant improvement in the 17-Item Hamilton Depression Rating Scale and the Center for Epidemiologic Studies Depression Scale ratings compared with both baseline (P<.01) and 6 weeks of placebo treatment (P<.01). A 50% or greater reduction in baseline Hamilton Depression Rating Scale scores was observed in 23 subjects after DHEA and in 13 subjects after placebo treatments. Six weeks of DHEA treatment also was associated with significant improvements in Derogatis Interview for Sexual Functioning scores relative to baseline and placebo conditions.”

Additional Benefits: DHEA and Sexual Function

So, in addition to making you feel happier, DHEA has also been found to help enhance sex drive as well. A year-long medical research study on DHEA and sex drive appears in an article on the Life Enhancement website.

What is evident from the research findings is that higher DHEA levels allow women to feel mentally sharp, more focused, have softer more hydrated skin and get deeper sleep at night. Thus they feel rested, have more energy and feeling of well-being. So naturally, when all these things are combined, you feel great on the inside and look great on the outside, sex drive comes back. Logically, this makes perfect sense.

In another study available on the National Institute of Health Pubmed website, 280 healthy men and women ages of 60 – 79 were given DHEA, 50 mg, or placebo, daily for a year in a double-blind, placebo-controlled study. Results showed no harmful effects. Study participants experienced significant improvements in mood and other measures of physiological health and psychological health after taking DHEA. In addition to having more energy and being in a better mood, study participants also experienced improved sex drive.

The results of DHEA supplementation were clearly shown to improve sex drive in women and men, even though the DHEA was taken orally rather than using an absorbable cream, which has since been shown to be the best way to use DHEA.

The article on the Life Enhancement website about the benefits of DHEA can help you be more productive and generally healthier too: supporting cardiovascular health, immune response and reducing risks of cancer. This is because DHEA is the most abundant pro-hormone in the body.

DHEA For Mood: Elevate Your Mood with Twist 25 DHEA Cream

People who add DHEA to their daily routine have been found to have more energy and get more done. With your hormones in balance, you can think more clearly which daily routines easier and more enjoyable.

Medical research published in the Journal of Clinical Endocrinology and Metabolism also found that after psychological assessment following DHEA supplementation, there was a “significant enhancement of self-esteem with a tendency for improved overall well-being. Mood and fatigue also improved significantly.”

For best results it is best to use a DHEA supplement cream that is absorbed and processed in the skin, where it occurs naturally anyway. Twist 25 DHEA cream provides what the body makes naturally, bioidentical DHEA, where the body uses it, the skin.

Instead of taking pills every day, simply apply the skin cream to DHEA the right way, and be happier and healthier as a result. If your male or female past age 35, make Twist 25 DHEA cream part of your daily routine. It usually takes about 3 weeks of regular daily use of Twist 25 DHEA cream to begin to notice improvements.

Your Path to a Healthier, Happier Life

At Health2Go, we’re proud to offer Twist 25 DHEA cream to help support your body’s optimal functioning. No other DHEA cream has been researched, tested and improved with the same rigor as Twist 25. Just rub in a a couple of squirts of Twist 25 cream twice a day to regain youthful health and happiness.

Feel your best and look your best with Twist 25.



Peter Schmidt, MD, Robert C. Daly, MD, and Micki Bloch, MD, et al. “Dehydroepiandrosterone Monotherapy During Midlife Major and Minor Onset Depression” Feb 2005. Arch Gen Psychiatry. 2005;62(2):154-162. doi:10.1001/archpsyc.62.2.154. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/208294

P J Hunt, E M Gurnell, F A Huppert, C Richards, A T Prevost, J A Wass, J Herbert, V K Chatterjee. Improvement in Mood and Fatigue after Dehydroepiandrosterone Replacement in Addison’s Disease in a Randomized, Double Blind Trial. Dec 2000. Journal of Clinical Endocrinology and Metabolism. 85(12):4650-6.doi: 10.1210/jcem.85.12.7022. https://pubmed.ncbi.nlm.nih.gov/11134123/

DHEA Improves Sex and Helps Keep Woman in Love. Life Enhancement website

Baulieu ÉÉ, Thomas G, Legrain S, Lahlou N, Roger M, Debuire B, Faucounau V, Girard L, Hervy MP, Latour F, Leaud MC, Mokrane A, Pitti-Ferrandi H, Trivalle C, de Lacharrière O, Nouveau S, Rakoto-Arison B, Souberbielle JC, Raison J, Le Bouc Y, Raynaud A, Girerd X, Forette F. Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. Proc Natl Acad Sci 2000 Apr 11;97(8):4279-84. https://pubmed.ncbi.nlm.nih.gov/10760294/


Hugh R. Woodward, MHA

Hugh Woodward is President/CEO of Health2Go, Inc. Health2Go makes and sells Twist 25 DHEA cream.
Hugh has a BBA in Business Management from University of Texas in Austin, Texas and an MHA, Master of Science in Health Care Administration.

Hugh is a subject matter expert on DHEA dedicating the past 20+ years of his life to studying the medical research about it. Hugh started Health2Go, Inc. in 2007 to research and develop the safest most effective DHEA supplement cream that can be made.

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