Depression Naturally With DHEA Cream

Beat Depression Naturally With DHEA Cream

Not feeling really happy lately? In 2023, statistics show that 40 percent of adult men and women in the U.S. are experiencing depression and stress. This alarming statistic could elevate the risk of various health conditions, including heart disease and weight gain. Want to figure out something that works to get you on the right track again? We explore the benefits of using DHEA for depression.

Antidepressants often do not the best answer when it comes to mild depression for people 35 and up. Start with the basics, like doing something, making something, or interacting with other people. Consider natural alternatives like Twist 25 DHEA cream, which has shown promising results without the side effects of traditional antidepressant drugs.

DHEA level may have a lot to do with it. Scientific placebo-controlled medical research studies show that DHEA, dehydroepiandrosterone, is a natural solution. Moreover, DHEA has been linked to anti-aging benefits and improved muscle strength.

What Is DHEA? 

DHEA, dehydroepiandrosterone, is a naturally occurring prohormone. Among other things, it is a base building block for most hormones in the body that may help reduce mild symptoms of depression. DHEA is the most abundant foundation or base from which the body makes hormones.

DHEA levels increase from birth through adolescence and puberty and peak between ages 20-25, when we are “in our prime.” Then, DHEA hormone levels gradually decrease by about 2% per year after that. So, by age 35, the body produces about 20% less DHEA than when we were “in our prime” at age 25, and by age 50, we produce 50% less DHEA than we did in our twenties.

This gradual decline continues, affecting bone density, muscle strength, and overall vitality. This decline can lead to conditions like bipolar disorder and other mood-related issues.

Human DHEA for depression levels with age

Hence, it is not unexpected to discover that many adults between the ages of 35 and 65 begin to lack drive and vitality and feel tired or like they are losing their focus and fitness. Unfortunately, many physicians prescribe antidepressant drugs without first offering more fundamental approaches like DHEA cream.

How DHEA Helps With Depression

Each year, around 10% of adults in the United States (about 20 million people) are diagnosed with depression. Women are twice as likely as men to suffer from adult-onset midlife depression.

A loss of enthusiasm characterizes depression, a feeling washed out or “blah” such that performing simple everyday tasks seems difficult and a feeling like everyday pleasures are gone. Life can seem overwhelming and hopeless. There are many natural remedies that can help.

While there are many factors that may contribute to depression, a decline in hormone production is a major contributing factor. This is the reason that many women, after menopause, defined as cessation of ovulation and the associated hormone decrease, Report that they feel depressed twice as much as men of the same age who are experiencing andropause. Many ways are naturally affected by decreased hormone levels.

As the most abundant hormone base in the human body, DHEA is very important to many functions, such as mental sharpness, memory, focus, energy, and feeling of well-being. Scientific evidence indicates that DHEA exhibits significant antidepressant effects.

Providing the body with adequate levels of prohormone DHEA after age 35 makes sense. People with higher levels of DHEA have more energy, and thus get more done and are in a better mood.” Higher DHEA levels were linked to a reduction in depression symptoms in half of the study participants.

Research suggests that DHEA can treat depression and regulate mood and may help reduce some of the negative side effects of mild to moderate depression. A 2004 study found that DHEA effectively treats midlife-onset major and minor depression. This suggests that DHEA cream may be an effective alternative to prescription antidepressants.

Numerous clinical research studies are published and accessible on the web. Just search “dehydroepiandrosterone depression” to find numerous studies that show DHEA helps fight depression. Many of these studies are available on PubMed. The study performed at the National Institute of Mental Health in Rockville, Maryland, concludes, 

“We find DHEA to be an effective treatment for midlife-onset major and minor depression.”

In addition to helping alleviate depression symptoms, DHEA helps enhance mood, allowing us to live a happier, healthier, and more active lifestyle. DHEA has no dangerous side effects. There are few risks to using a DHEA supplement other than increased skin sebum or accelerated hair growth. These potential “negative side effects” are actually viewed as important benefits for most people.

How To Use DHEA for Depression

DHEA is primarily produced in the adrenal glands and gonads and metabolized in the skin’s dermis. That’s why it is crucial to use DHEA as an adequately made skin cream rather than a pill. DHEA absorbed in the skin is much more effective than oral DHEA supplements.

The liver eliminates oral DHEA supplements. So, all DHEA supplements only increase DHEA sulfate, not free DHEA. DHEA-S is less beneficial for your health or how you feel than Twist 25 DHEA cream.

Twist 25 DHEA cream should be applied to the skin every morning and evening. It is best to rub into thin, hairless skin. It leaves no smell or oily residue. Each full pump press from the pump contains 25 MG bioidentical DHEA. 

Twist 25 DHEA cream is a specially made bioidentical DHEA skin cream with a coconut oil base, vitamin E, and coenzyme Q-10. It’s one of the best things you can do past age 35 to maintain your hormones, health, mood, sleep quality, energy, muscle tone, cardiovascular health, skin health, and immune system. DHEA is the most abundant prohormone in the human body and does a myriad of beneficial things in the body with no dangerous side effects. Twist 25 DHEA for depression cream makes you feel focused and alive.

Natural Remedies for Depression

Putting things together for a well-rounded perspective on overall health and happiness is important. Twist 25 DHEA cream should be included as a convenient part of many things that work together to keep us healthy and happy past age 35.

Numerous medical research studies show that eating a healthy diet, drinking plenty of water, and sleeping at least 7-8 hours per night are some other important basic first steps. With regard to a healthy diet, many people need more magnesium or vitamin B6 in their diet.

Vitamin B6 is needed to allow the production of neurotransmitters serotonin and dopamine. Some good sources of magnesium include legumes, nuts, whole grains, and green vegetables. Like vitamin B6, magnesium is needed for the production of serotonin.

Other important natural ways to improve mood are to stay active and get at least 30 minutes to an hour of exercise every day as a major contributor to staying healthy and having a positive outlook.

Another thing that many people forget is that moderate exposure of skin to sunlight every day has been shown to increase levels of vitamin D3, which is a pro-vitamin facilitator in many of the same ways DHEA is a prohormone. Getting sunlight on the skin is a good thing. Sunshine has been shown to help keep us happy.

Another natural remedy for depression is omega-3 fatty acids. It is widely known now that omega-3 oils are very important for proper brain function. The body cannot make Omega-3 fatty acids, so they must be ingested in the diet.

Foods such as salmon or sardines contain some of the highest amounts of omega-3 fish oils. Interestingly, countries where people eat high levels of such rich omega-3 oil, have the lowest levels of depression.

Twist 25 Cream

There are many components that together give us our health and happiness. Using DHEA correctly is just one helpful part of the overall picture. All the little things we do daily combine to make us who we are. Eat a healthy diet, drink lots of water, get at least 7-8 hours of sleep every night, exercise daily, and maintain healthy hormones to fight depression naturally.

According to Dr. John R. Woodward, the inventor of Twist 25 DHEA cream, 

“It does make sense: The reason DHEA would have these antidepressant effects is because DHEA is the most abundant prohormone in the body, a naturally occurring base building block for hormones. DHEA the right way. Method of administration: a special skin cream.” 

Known today as Twist 25 DHEA cream.


Below, you’ll find links to some of the medical research discussed in this article, accessible on the web:

Wolkowitz OM, Reus VI, Roberts E, et al “Dehydroepiandrosteron (DHEA) Treatment of Depression” Department of Psychiatry, University of California, San Francisco, School of Medicine 94143-0984, U.S.A. Feb 1, 1997

Schmidt PJ, Daly RC, et al “Dehydroepiandrosterone monotherapy in Midlife-onset Major and Minor Depression” Behavioral Endocrinology Branch, National Institute of Mental Health, Rockville, MD 20892-1276, U.S.A. Feb 2005

G. Valenti, L. Ferrucci, F. Laurentani, G. Ceresini, S. Bandinelli, M. Luci, G. Ceda, M. Maggio, and R.S. Schwartz “Dehydroepiandrosterone sulfate and cognitive function in the elderly. The InCHIANTI Study” Journal of Endocrinology Invest. Oct 2009: 32(9): 766-772

Stephenson K, et al “The Effects of compounded bioidentical transdermal hormone therapy on hemostatic, inflammatory, immune factors; cardiovascular biomarkers; quality of life measures;and healthoutcomes in perimenopausal and postmenopausal women.” Womens Wellness Center, Tyler, Texas, U.S.A. Feb 17, 2013

Clarke JL, Skoufalos A, Medalia A, Fendrick AM. Improving health outcomes for patients with depression: a population health imperative. Report on an expert panel meeting. Population Health Management. 2016;19(S2):S-1-S-12. doi:10.1089/pop.2016.0114

Hugh R. Woodward, MHA

Hugh Woodward is President/CEO of Health2Go, Inc. Health2Go makes and sells Twist 25 DHEA cream.
Hugh has a BBA in Business Management from University of Texas in Austin, Texas and an MHA, Master of Science in Health Care Administration.

Hugh is a subject matter expert on DHEA dedicating the past 20+ years of his life to studying the medical research about it. Hugh started Health2Go, Inc. in 2007 to research and develop the safest most effective DHEA supplement cream that can be made.

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