How to use DHEA

Want to know how to use DHEA? DHEA should be used as a properly made pharmaceutical grade bioidentical DHEA cream called “Twist 25” instead of a pill.

DHEA stands for dehydroepiandrosterone, which is the most prevalent naturally occurring pro-hormone in the human body. Unlike foreign substances, it’s a natural hormone precursor unique to humans. In this article, we delve into the essential difference between DHEA creams and pills, explaining why an absorbable DHEA cream supplement is not just more effective but also safer. It aligns with what your body naturally uses and is delivered directly where it is processed by the body, the skin or dermis.

For people 35 and up, Twist 25 DHEA supplement cream is the best way to maintain healthy hormones and enjoy the various health and psychological benefits DHEA offers.

DHEA was first identified in 1931 by Dr. Adolf Butenandt, who was awarded the Nobel Prize for Chemistry in 1939. Frequently called “the anti-aging hormone”, DHEA is a base for more than 50 hormones that are smaller or more specific carbon chain molecules in human biochemistry. As a precursor for all estrogenic and androgenic hormones, humans make DHEA naturally from birth.

DHEA is the most abundant foundation or base from which the body makes hormones. DHEA is produced and metabolized in the adrenal glands, gonads, and dermis. This is why using DHEA as an absorbable skin cream makes sense, rather than swallowing a DHEA pill.

It is important to understand why using DHEA as a properly made absorbable skin cream rather than a pill makes sense. Twist 25 DHEA cream is a pharmaceutical grade absorbable DHEA delivered by a special coconut oil base cream. Let’s explore the science.

DHEA levels over the human lifespan

DHEA levels increase from birth through adolescence and puberty and peak between ages 20-25, when we are “in our prime”. Then DHEA levels gradually decrease by about 2% per year thereafter. So, by age 35, the body produces about 20% less DHEA than when we were “in our prime” at age 25; and by age 50, we produce 50% less DHEA than we did when we were in our twenties. This gradual decline continues.

 

 

 

 

 

 

 

 

 

 

Men and women produce more and more DHEA every year to about age 25 when levels are at their peak. After age 25, DHEA levels begin to decline at a rate of about two percent per year thereafter.

Checking your DHEA levels is a straightforward process. Simply visit a lab and request a DHEA test. You don’t need a physician’s order for this; just walk in and ask. Within a day or two, you’ll have your results.

You can also opt for a comprehensive hormone profile for either gender, which will include your levels of estrogenic and androgenic hormones. These results will come with a normal range based on your age for reference. It’s worth noting that labs typically measure DHEA sulfate (DHEA-S) because it offers a more consistent indicator compared to free DHEA, which can vary throughout the day.

What does DHEA do?

One of the primary roles of DHEA is as a base hormone precursor. DHEA also supports the immune system, allowing for a greater number of and activity of natural killer (NK) cells. Low DHEA levels are associated with many diseases of aging, such as cardiovascular disease, cancer, osteoporosis, depression, and dementia.

DHEA promotes tissue formation after exercise, and counterbalances the inflammatory effects of cortisol. So it helps reduce soreness after workouts and helps us rebuild muscle, cartilage and bone. DHEA also serves as a base for sebum (skin oil), protecting skin cells from both UV and chemical carcinogens. In addition, DHEA stimulates the formation of connective tissue and cartilage and improves bone strength.

DHEA supports:

• Energy, focus and mental acuity
• Immune system
• Lean muscle tone
• Bone strength
• Cardiovascular health
• Libido and sexual performance
• Deep REM sleep
• Softer, more hydrated skin

DHEA reduces:

• Abdominal Fat
• Risk of Cancer
• Risk of Cardiovascular Disease
• Fatigue
• Depression
• Poor quality sleep
• Joint pain
• Muscle soreness

It is not possible to eat any particular foods to increase DHEA. DHEA supplementation is generally recommended for people 35 and up to maintain health.

Listen to the Health2Go podcast on why DHEA Cream is an important Health Strategy. We explain what DHEA is and why supplementing DHEA using a properly made absorbable skin cream called Twist 25 is great for women and men 35 and up. Benefits include cardiovascular health, immune system support, counterbalancing cortisol, the stress hormone, reducing fat and inflammation… Listen here.

DHEA cream vs pills: Why Twist 25 DHEA cream works

As mentioned above, the human body naturally metabolizes DHEA in the dermis. Twist 25 cream provides what the body uses naturally, bioidentical DHEA, where the body uses it, in the dermis or skin, the largest organ of the human body. Twist 25 cream yields noticeable benefits within a few weeks. DHEA is much less effective when taken as a pill because most DHEA is eliminated by the liver.

Twist 25 DHEA Cream Instead of a Pill

There are 3 key medical reasons for this:

1. First-pass effect

When DHEA is taken orally as a pill, most DHEA is eliminated by the “First-pass effect” of the liver. Basically, the liver filters out most of the effective DHEA before it can do any good; and what does end up increasing in the bloodstream is DHEA-S (DHEA sulfate), not free DHEA. Free DHEA is truly the base from which the sex hormones are metabolized. These androgenic and estrogenic hormones are the hormones that help us to feel good.

 

 

 

 

 

 

 

 

 

 

2. DHEA-S is not the same as free DHEA

DHEA-S is not the same as free DHEA and cannot be converted by the body into free DHEA. DHEA can be converted into DHEA-S, but not the other way around. There is an excellent medical research study that explains why.

(Hammer, Fabian, Subtil s, Lux P, Maser-Gluth C, Stewart P, et al “No Evidence for Hepatic Conversion of Dehydroepiandrosterone (DHEA) Sulfate to DHEA: In Vivo and In Vitro Studies” Journal of Endocrinology and Metabolism. March 8 2005 pp 3600-3605) http://jcem.endojournals.org/content/90/6/3600.full.pdf

3. DHEA Metabolizes in the Skin

Medical research shows the human body metabolizes most DHEA into various smaller, more specific hormones in the skin (the dermis). The skin is where we metabolize much of the DHEA we make. So Twist 25 DHEA cream actually provides exactly what the body produces naturally, bioidentical DHEA, where it can be utilized, the skin. DHEA also has many skin-care benefits because DHEA is a base for sebum, helps with collagen formation, and protects skin cells from both UV and chemical carcinogens.

Dr. Fernand Labrie and his research team at Universtity of Toronto School of Medicine discovered and named a new field of medicine called “intracrinology”. Intracrinology is the study of the intracellular actions, regulation, trafficking, and interactions of extracellular signaling peptides/proteins, like DHEA.

“In postmenopausal women, all estrogens and most androgens are made locally in peripheral target tissues from the adrenal steroid precursor dehydroepiandrosterone (DHEA). In adult men, approximately 50% of androgens are made locally.” So, in other words, a great deal of DHEA metabolism happens inside skin cells when DHEA is rubbed into the skin. It is processed inside the cells of the dermis.

(Labrie F. et al Semin Reprod Med. 2004 Nov;22(4):299-309. Adrenal androgens and intracrinology.

Source: Oncology and Molecular Endocrinology Research Center, Laval University Hospital Research Center, Quebec City, Canada. [email protected])

Financial Reasons DHEA Cream Is Better Than Pills

There are also financial reasons a properly made DHEA cream like Twist 25 DHEA cream, is better than pills:

#1 Twist 25 DHEA cream cost a bit more than a bottle of DHEA supplement pills; but since DHEA cream provides free DHEA in the dermis, which serves as a base hormone precursor for the sex hormones, the physiological health benefits from using the cream instead of the pills are significant. 

Twist 25 DHEA cream benefits can be felt within a few weeks due to the superior method of delivery of DHEA in the skin. Yes, Twist 25 DHEA cream is a bit more expensive than a bottle of DHEA pills, but the benefits for for health and how you feel and look are worth it.

#2 Think of the cost versus benefit of improved cardiovascular health versus having a heart attack. Think of the savings obtained from a stronger immune system that allows you to avoid medications and time off from work if you got sick instead. Think of the improvements in quality of life and health from sleeping soundly at night.

Meanwhile, when DHEA is applied on the skin where it occurs naturally anyway, you avoid the burden on the liver that must filter out the DHEA pills when swallowed orally. Most of the effective DHEA is eliminated by the first pass effect of the liver when DHEA is taken as a pill.

Yes, DHEA pills are cheap; but if they don’t do you any good, what’s the point? So, the cost versus benefit of using DHEA cream with much better bioavailability achieves much better results leading to improved physiological and psychological health and reduced health care costs in the long run.

Application: How To Apply DHEA Cream

So instead of wasting time and money on DHEA pills that have little or no noticeable benefit, use Twist 25 DHEA cream by rubbing it into thin hairless skin where it absorbs quickly into the dermis and leaves no residue or odor. DHEA the right way.

Twist 25 DHEA cream is made with a pharmaceutical-grade coconut oil base cream and also contains coenzyme Q-10 and vitamin E. It contains all plant-sourced ingredients. It has no parabens, no lecithin; no cyclodextrin. No dangerous side-effects.

DHEA is the same hormone precursor in men as it is in women. It is simply a base that the body uses however it needs to. Obviously, men process it into different hormones than women do.

The body uses free DHEA as a precursor to the sex hormones, whereas DHEA sulfate does not. This is why people feel and notice the benefits of using Twist 25 DHEA cream instead of pills.

Twist 25 DHEA cream does cost a bit more than DHEA pills or imitation products. This is because Twist 25 DHEA cream contains pharmaceutical-grade ingredients compounded in an FDA-approved facility into a highly specialized cream that is tested for proper mix and strength. 

How To Use DHEA: Suggested use

Each full pump press from the Twist 25 pump contains 25 MG DHEA. Noticeable benefits of DHEA cream begin to be felt within a few weeks of regular daily use.

DHEA is safe, is not addictive or habit-forming and has no dangerous side effects. DHEA is the most abundant naturally occurring prohormone in the human body.

Twist 25 DHEA cream is typically recommended for individuals aged 35 and older. However, it hasn’t been tested for use by pregnant or nursing women. Rest assured, it boasts a profile free of dangerous side effects. 

Manufactured and sold exclusively in the U.S.A., Twist 25 DHEA cream can be purchased without a prescription. However, in countries like Canada, France, and Australia, DHEA-containing products do require a prescription from a physician. Please note, Health2Go, Inc. can only process orders if both the billing and shipping addresses are within the U.S.A.

It is important to use Twist 25 DHEA cream properly to get the many benefits DHEA can provide. The best results are achieved by consistent daily use of the cream. Application once in the morning and once in the evening is recommended because Twist 25 DHEA cream has a half life of 10 hours.

It is helpful to apply the cream after a warm bath or shower when skin is clean and completely dry. After a warm shower or bath pores are open and blood flow is maximized. Avoid swimming or washing the cream off for at least the first few hours after application.

The Importance of a Daily Routine

Make Twist 25 DHEA cream part of your daily routine. It is good to apply the cream after a warm bath or shower when skin is clean and dry. Skin pores are open and clean and blood flow is good.

As a convenient reminder, just put the bottle right by your sink near your toothbrush and toothpaste. Just put on some Twist 25 cream every time you brush your teeth.

 

 

 

 

 

 

Do this at least morning and evening every day. Twist 25 DHEA cream is for external use. Avoid sensitive skin near eyes or mouth. Twist 25 DHEA cream is for application as a topical skin cream.

As summarized by Dr. John Woodward, M.D. “DHEA must be used as a bioidentical DHEA cream called Twist 25. Use Twist 25 DHEA cream. Make your own hormones.”

User Testimonials

“This cream has been remarkable for me! I’m 55 and was struggling BIG TIME… with lack of well being, lack of energy and lack of libido. From the first pump, I noticed something … albeit very small.. but within 3 weeks I am a different woman! I don’t feel the need for naps, my well being is restored and my libido better than ever! This product is the REAL DEAL! I’m so thankful to have found this product!“

–Female, Age 55, Mont Vernon, New Hampshire

“DHEA is the most abundant base for hormones in our body. It is not a foreign substance. We make it and have it in our systems naturally. So keep DHEA levels where they are when we are healthiest. It just makes sense.”
– Female, Medical Doctor, Dallas, Texas, Age 47

“I have received a wonderful blessing… Twist 25! I know some people throw around the phrase ‘blessing’, but I don’t. I finally am getting my life back. Here is a list of some of the great changes I have experienced so far: energy & depth, Results when I work out, Faster recovery after workouts, Feeling of “centeredness” or “well-being” in everyday life, soft hydrated skin, healthy hair, fast-growing fingernails, mental clarity, consistent sex drive, sound sleep

I‘ve been using Twist 25 for 5 years. I look forward to getting up every day, working out, and living a happier, healthier life!”

– Female, Julie W., Demoines, Iowa, Age 42

“I started using Twist 25 about 6 months ago, and it’s great. I started on a new health kick. Seems like I’m making more of life. I feel great… About 3 weeks after I started using Twist, I started exercising more and going to the gym ‘ I had a drive to do it – I worked out with my weights some, jogged a few times more than I usually do, and …..that’s it. I feel great. I’m productive at work. I sleep better at night. Twist 25 helps me thrive. It keeps me at my best.”
– Male, Age 43

“I have been using DHEA cream for 4 years and believe it has had an impact on the overall condition of my body at this age. I work out 4 times per week now. No one in the gym can believe I just turned 55 (she laughs). I have less than 10% body fat, and my muscles are defined…see (laughing)..and this guy at the gym told me I have the body of a 30-year-old.”(deep smile)
– Female, Marketing Consultant, Age 56

“I have been using Twist 25 for 4 years and I feel great and have more energy, and my skin is softer. I feel fit and trim and don’t have to work out as much as I used to to stay in shape. Also, I recover faster after my workouts and benefit more. I have more energy, and I’m leaner. It’s amazing. I love it!”
– Female, Designer and Fashion Model, Age 49

“I’m 72 years old and have been taking DHEA for eleven years. My wife has been using DHEA for 18 years. We don’t take it for any major effect. It’s lots of subtle effects, not dramatic… DHEA is basic. The question is not whether we are going to live longer from DHEA supplementation. The question is: Will we live in a youthful state day to day? DHEA helps us maintain a higher quality life.”
– William Regelson, M.D. professor of medicine at the Medical College of Virginia

Where to Begin Using Twist 25: How to use DHEA cream

As explained above, to benefit from DHEA supplementation and actually feel the benefits, it is crucial to use DHEA the right way, as an absorbable skin cream. To begin using Twist 25 DHEA cream, stop using DHEA pills. Twist 25 DHEA cream is available to buy online as well as from many health care providers and health supplement retailers in the USA.

Twist 25 DHEA cream is a bit more expensive than oral DHEA supplement pills. This is because Twist 25 DHEA cream is made with top quality pharmaceutical grade ingredients in a facility following good manufacturing practices, GMP, and following all requirements of the FDA. Twist 25 DHEA cream is laboratory tested to meet microanalysis standards and proper mix. Don’t be fooled by cheap imitation products.

Apply one or two pump presses of Twist 25 DHEA cream onto thin hairless skin and rub in until the cream absorbs completely. Each full pump press from the pump bottle contains 25 MG pharmaceutical grade bioidentical DHEA.

Make it part of your daily routine. Twist 25 DHEA cream should be applied morning and evening every day. Twist 25 DHEA cream is for external use.

As mentioned above, it is good to apply the cream after a warm bath or shower when the skin is clean and dry; skin pores are open and clean, and blood flow is good. Avoid sensitive skin near the eyes or mouth.

FAQs about DHEA Cream

Making the right choice with Twist 25 DHEA cream

DHEA must be used the right way to provide the many health benefits it can provide. It should be used as a properly made absorbable skin cream to work. Twist 25 DHEA cream is generally recommended for men and women aged 35 and up. Twist 25 DHEA cream has no dangerous side effects.

Use Twist 25 DHEA cream to maintain hormone balance to feel your best and look your best. As the inventor of Twist 25 DHEA cream, Dr. John Woodward, M.D., said, “DHEA must be used as a bioidentical DHEA cream called Twist 25. Use Twist 25 DHEA cream. Make your own hormones.”

References:

• Labrie F. et al Semin Reprod Med. 2004 Nov;22(4):299-309. Adrenal Androgens and Intracrinology. Source: Oncology and Molecular Endocrinology Research Center, Laval University Hospital Research Center, Quebec City, Canada. [email protected]
• Hammer, Fabian, Subtil S, Lux P, Maser-Gluth C, Stewart P, et al “No Evidence for Hepatic Conversion of Dehydroepiandrosterone (DHEA) Sulfate to DHEA: In Vivo and In Vitro Studies” Journal of Endocrinology and Metabolism. March 8 2005 pp 3600-3605) http://jcem.endojournals.org/content/90/6/3600.full.pdf

• Labrie, Fernand, Labrie C, “DHEA and intracrinology at menopause, a positive choice for evolution of the human species” Source: Climacteric – The Journal of the International Menopause Society. 2013 Apr;16(2):205-13. doi: 10.3109/13697137.2012.733983. Epub Nov 5, 2012. Pubmed https://pubmed.ncbi.nlm.nih.gov/23126249/