The Truth About DHEA - DHEA is safe

DHEA The Big Picture

So if you’re like most people, you want to do your homework before you start using a new health supplement.
You definitely should.
Let’s look at all the pro’s and con’s. Consider all the facts. Consider the science. What do the medical research studies show?
What are the benefits of DHEA and what are the possible risks or dangers?
Are there dangerous side effects? What good can it do for me?
It is good to think things through.  Consider all the facts.
What do we know about DHEA ? What is DHEA? Why should men and women 35 and up use Twist 25 DHEA skin cream every day ? Why bother?

What is DHEA?

Let’s talk about DHEA, or dehydroepiandrosterone, to use its full name. This hormone precursor, or pro-hormone, can be thought of as the ‘building block’ for our bodies. It’s a large carbon chain molecule (19 carbon) that serves as a base foundation for the production of other, smaller molecules, known as hormones like testosterone and the estrogens. The adrenal glands, gonads, and dermis are in produce and process DHEA into what particular hormones the body needs.

DHEA was first isolated and identified in 1931 by Dr. Adolf Butenandt, who was awarded a Nobel Prize in Chemistry. DHEA is often called the “the mother of all hormones” or “the anti-aging hormone”, or “the fountain of youth hormone”. DHEA is the precursor for over 50 smaller more specific carbon chain molecules or hormones. It serves as a base foundation for all estrogenic and androgenic hormones. From birth, our bodies naturally produce DHEA. DHEA is not a hormone found in animals. DHEA only occurs in humans.

Interestingly, the production of DHEA increases year by year from birth until we reach about age 25, when levels are at their highest. between the ages of 18-35 we are making the most DHEA. Notice that these are the years when human beings are most physically and mentally fit. These are the years when nature calls, and couples have children. It makes sense. Following that, the levels of DHEA begin to drop approximately 2% per year.

dhea levels with twist 25

#1 Is DHEA Safe?

Yes. DHEA is as natural for our bodies as sunlight or water. DHEA has no known dangerous side effects. This supplement has been used by the general public in the USA for more 40 years, and there are no dangerous side effects.

What does DHEA do?

DHEA serves as a precursor to various hormones, which are essentially your body’s chemical couriers, ensuring it works like a well-oiled machine. Additionally, DHEA is a major player in bolstering your immune system. It accomplishes this by stimulating the action of natural killer (NK) cells. A deficiency in DHEA is often linked with several age-related illnesses, encompassing heart disease, cancer, osteoporosis, melancholy, and dementia.

DHEA promotes tissue formation. So after exercise, DHEA counterbalances the inflammatory effects of cortisol. So it helps reduce soreness after workouts, and helps us to rebuild muscle, cartilage and bone. DHEA also serves as a base for sebum (skin oil), protecting skin cells from both UV and chemical carcinogens. In addition, DHEA stimulates formation of connective tissue and cartilage and improves bone strength.

health benefits of dhea
benefits of dhea
DHEA is important for many aspects of physical and psychological health and well-being. Here are some key things DHEA does:

Comprehensive Health Benefits of DHEA:

DHEA reduces:

It is not possible to eat any particular foods to increase DHEA. DHEA supplementation is generally recommended for people 35 and up to maintain health.

Why Consider DHEA Supplementation?

After age 25, our natural DHEA levels decline. Restoring those levels can have a profound impact on how we feel and function. DHEA helps us:

  • Maintain Energy & Vitality: Supports the drive and energy needed to live life to the fullest.
  • Stay Active & Healthy: Contributes to stronger bones, muscles, with healthier skin and less fat.
  • Maintain cognitive function, visuospatial awareness and psychological well-being.

DHEA Dosage and Suggested use

DHEA is safe; it is available in the USA without a prescription. DHEA is not addictive or habit forming.
It is very important to use DHEA properly to yield the many benefits DHEA can provide. When taken orally as a pill, most DHEA is eliminated by the liver before it can have any beneficial effects. DHEA should be used as a properly made skin cream that is absorbed in the skin rather than ingesting it orally as a pill for absorption through the digestive tract.
Don’t waste your time and money taking DHEA pills, or cheap ineffective cream imitations. Twist 25 DHEA cream is a pharmaceutical grade bioidentical DHEA cream made with ingredients from plant sources with a coconut oil cream base.
Twist 25 DHEA cream is the best quality DHEA supplement available. One full pump press of Twist 25 DHEA cream contains 25 MG DHEA. Suggested use: Apply 1-2 pump presses morning and evening each day. Rub in completely between inner arm and abdomen. Twist 25 DHEA cream is best absorbed on thin hairless skin.
Noticeable results begin to be felt after 3-4 weeks of daily use.
Use Twist 25 cream. Make your own hormones to feel your best and look your best.

So should someone 35 or older use Twist 25 DHEA cream every day?

Consider all the positive beneficial reasons it is known to be good for physiological and psychological health. DHEA has no dangerous side effects. DHEA is the most abundant naturally occurring hormone in the body and is known to decrease after age 25 at a rate of about 2% per year.
Why would I use something daily that I don’t have to? To feel and function better and maintain the greatest quality of life I can as I get older. Stay active. Stay at your best. There is no reason not to.
Twist 25 DHEA cream is something added to the daily routine that does a long list of beneficial things and does no harm.
It’s become increasingly popular among health professionals across the globe to consider DHEA levels, along with the ratio of DHEA to cortisol, as a pivotal gauge for judging one’s overall mental and physical health. In fact, measures of these two hormones have become a cornerstone evaluation method for overall health and well-being in the U.S. Military. To give you a specific instance, novel medical research that’s been conducted on U.S. Navy SEALs candidates going through the rigorous BUDS training, employs DHEA levels as a key determinant of their physiological and psychological health, quite fascinating, don’t you think?

DHEA for Exercise Results

DHEA supplementation enhances exercise performance. Professional and Olympic athletes are prohibited from using DHEA supplements because use would provide advantages in health and fitness.

So, as long as you are not competing in professional sports or competing in NCAA or Olympic events, you probably want a health advantage!

  • Promotes cell formation for connective tissues such as muscle, cartilage and connective tissue, bone osteocytes as well as skin cells in the dermis, and neurons as well.
  • Allows for healthier epithelial cells throughout the cardiovascular system and peripheral tissues.
  • Is a base or precursor to 50 hormones as well as sebum that is a natural moisturizer for skin and hair.
  • Counterbalances the inflammatory effects of cortisol. So, after workouts muscle recovery is improved while soreness is reduced DHEA allows formation of shapelier, toned muscle.
  • Has been shown to reduce both subcutaneous and visceral abdominal fat because DHEA improves the ability to burn energy rather than storing it away as fat.

Beyond Athletic Benefits

DHEA is a crucial hormone precursor for male and female sex hormones that humans produce naturally from birth. Men and women make greater amounts of DHEA every year until about age 25 when levels are at their peak. This is also when humans are in reproductive prime, at their peak of physical health. After age 25, DHEA levels begin to decline at a rate of about 2% per year.

DHEA should be supplemented via proper method of use to yield noticeable benefits. Using DHEA correctly as a specially made skin cream yields more favorable benefits compared to DHEA in pill form which is far less effective. After regular daily use for 3 weeks one can actually feel noticeable benefits, whereas DHEA pills are far less effective.

People 35 years and older (who are not competing as a professional or Olympic athlete) should apply Twist 25 DHEA cream daily.

Twist 25 DHEA cream is available without a prescription. It is not addictive or habit forming. Twist 25 cream has no dangerous side effects. It is made with a special cream base containing coconut oil, vitamin E and coenzyme Q10. It contains no petroleum byproducts, no soy, no lecithin, no paraben, no cyclodextrin.

There are no particular foods to eat that will increase DHEA levels. For greatest benefit, people 35 or older apply Twist 25 DHEA cream on thin hairless skin each day.


So when you take all the medical research into consideration, you can understand the big picture.

Daily application of Twist 25 DHEA cream on the skin is simply augmenting the DHEA produced naturally. It’s a little bit of a good thing that does many beneficial things in the body and has no dangerous side effects. Eating a healthy diet and exercising daily allows the benefits to be noticed more.

Beneficial improvements continue over the course of several months; and many Twist 25 users have been using the cream for more than 20 years. So be patient, and be realistic. No, it won’t have you jumping tall buildings in a single leap overnight. It’s not magic. It is simply a very good natural skin cream to help you maintain health and mood every day, and has no dangerous side effects. Using Twist 25 DHEA cream just makes sense.

Health2Go, Inc. is proud to offer Twist 25 DHEA cream to help men and women 35 and up to live healthier happier lives. DHEA cream is tested and perfected to be the top-quality DHEA cream.

Twist 25 DHEA cream can help maintain physiological and psychological health and quality of life. Use Twist 25 DHEA cream to feel your best and look your best.

It’s all the little things we do each day consistently that make a big difference.

Twist 25 DHEA cream can help you feel your best and look your best. Use Twist 25 DHEA cream. Make your own hormones.


Peter Schmidt, MD, Robert C. Daly, MD, and Micki Bloch, MD, et al. “Dehydroepiandrosterone Monotherapy During Midlife Major and Minor Onset Depression” Feb 2005. Arch Gen Psychiatry. 2005;62(2):154-162. doi:10.1001/archpsyc.62.2.154.

“DHEA Lessens Depressive Symptoms, NIMH Study Shows” Psychiatric Times Vol 21 No 8, Volume 21, Issue 8, July 1 2004.

Sean P. Prall, Michael P. Muehlenbein. “DHEA Modulates Immune Function: A Review of Evidence”. Vitamins and Hormones. 2018 Elsevier Inc.
ISSN 0083-6729.

Friess E, Trachsel L, Guldner J, Schier T, Steiger A, Holsboer F. “DHEA administration increases rapid eye movement sleep and EEG power in sigma frequency range.”  American Journal of Physiology Jan 1995 268(1 Pt 1):E107-13. Pubmed study

Hugh R. Woodward, MHA

Hugh Woodward is President/CEO of Health2Go, Inc. Health2Go makes and sells Twist 25 DHEA cream.
Hugh has a BBA in Business Management from University of Texas in Austin, Texas and an MHA, Master of Science in Health Care Administration.

Hugh is a subject matter expert on DHEA dedicating the past 20+ years of his life to studying the medical research about it. Hugh started Health2Go, Inc. in 2007 to research and develop the safest most effective DHEA supplement cream that can be made.

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